100% committed to ending dementia. For good.

All in to end Alzheimer disease.

CLEAR is the only Canadian foundation that directs 100% of funds raised to promising scientific research into the cause, prevention, and treatment of Alzheimer disease and other dementias.

Because it’s clear: the only path to a cure is more research.



people living with dementia in Canada

Even more alarmingly, by 2031 this number is expected to exceed 1 million.


research projects funded by CLEAR

Each of these projects has contributed to our collective understanding of dementia.


leading cause of death in Canada

Every year, over 6,000 Canadians die from the disease. That’s 16 loved ones lost each day.


of funding provided to researchers

We will keep funding promising research until we have the cure the world has been waiting for.

Past & Present Research

The development of comparison standards for the cognitive measures employed in Canadian Longitudinal Study on Aging

Q: What did we learn? Dr. Tuokko has provided a clear set of empirical baseline for what can be considered healthy cognition for French- and English-speaking Canadians, and what would be considered concerning. This is vital information to have for the diagnosis of dementia for Canadians. Q: Why is this knowledge important? With the ability…

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Contribution of microglia activation and neuronal oxidative stress to Alzheimer’s disease

ABSTRACT Recent studies have indicated that microglia, our protective immune cell in the brain, might be important in causing the loss of nerve cells in Alzheimer disease. To further understand these processes, we will study how microglia cause oxidative stress, a phenomenon that causes an over production of reactive oxygen radicals. We recently found that…

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Validation of Connexins and Pannexins as a target for Alzheimer’s Disease

ABSTRACT Alzheimer’s Disease (AD) is the most common cause of dementia, accounting for over two thirds of cases. There are currently no successful treatments, making the discovery of effective therapeutic interventions critical. The brain contains billions of neurons, and substantially more non-neuronal cells called glia; the major ones relevant to this proposal are astrocytes. While…

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Non-invasive imaging of Alzheimer Disease biomarkers in the brain and eye

ABSTRACT Age related neurodegenerative diseases such as Alzheimer’s Disease (AD) affect ~500,000 Canadians, and the economic burden of dementia was $15 billion in 2008. Early diagnosis and novel therapies are needed to improve the quality of life of affected individuals, and to reduce costs to the Canadian health care system. However, screening for irreversible hallmarks…

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Together, we can find a cure for Alzheimer disease.

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