Our Research
Funding world-class research that sparks hope
CLEAR Foundation's singular mission is funding world-class dementia research in Canada.
From advancing early diagnosis to pioneering new treatment innovations, our funded scientists are at the forefront of uncovering research breakthroughs right here in Canada.
Our Funded Research
By funding high-impact biomedical research, CLEAR Foundation empowers leading scientists to push boundaries, accelerate discoveries, and bring us closer to a future free from dementia.
Every grant we award fuels innovation, collaboration, and hope, ensuring that Canada remains at the forefront of global dementia research.
With the support of our donors, we are driving progress across the entire research spectrum: from prevention and early detection to life-changing treatments and the ultimate goal of discovering a cure.
Explore our present and past research projects:
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017
Dr. Dustin King
O-GlcNAc's role in protein stability
Dr. Debra Sheets
Voices in Motion: An intergenerational community choir to support social inclusion and quality of life for persons with Alzheimer's disease and their caregivers
2016
Dr. Haakon Nygaard
Chemical suppression of nonsense mutations for the treatment of Frontotemporal dementia
Dr. Arya Mehran
Neurally-produced estradiol enhances the neuroprotective actions of insulin
Dr. Holly Tuokko
The development of comparison standards for the cognitive measures employed in Canadian longitudinal study on aging
2015
Dr. Vedrana Cvetkovska
The mechanism and significance of the synaptogenic activity of amyloid precursor protein
Dr. Yun Zhang
Human islet amyloid polypeptide aggregation, the missing link between Type 2 diabetes and Alzheimer's disease
Dr. Sieun Lee
Are there indicators of Alzheimer's disease in the eye?
Dr. Brett Eyford
Assessment of melanotransferrin as an Alzheimer's disease biomarker
Dr. Cindy Barha
Effect of aerobic exercise on cognitive decline and brain region volumes in older men and women with mild cognitive impairment
Dr. Jasmin Hefendehl
Altered glutamate dynamics in a mouse model of Alzheimer's disease
2014
Dr. Mirza Faisal Beg
Novel retinal biomarkers for Alzheimer's disease
Dr. Neil Cashman
Targeting amyloid propagation in Alzheime's disease: Structures, immunology and extracellular vesicle topology
Dr. James Johnson
Locally produced brain insulin in memory and Alzheimer's disease: A multi-disciplinary approach to a key question
Dr. Christian Naus
Validation of connexins and pannexins as a target for Alzheimer's disease
Dr. David Vocadlo
Preclinical development of a disease modifying small molecule therapy for Alzheimer's disease
Dr. Marinko Sarunic
Non-invasive imaging of Alzheimer's disease biomarkers in the brain and eye
Dr. James Johnson
Can the loss of brain-derived insulin cause Alzheimer's Disease
2013
Dr. William Jia
Stress-related cytoplasmic TDP-43 aggregation
Dr. Robin Hsiung
Characterization of dementia due to mixed AD and subcortical vascular pathology
Dr. Cheryl Wellington
Revisiting the vascular contribution to AD
2012
Dr. Bryce Mulligan
Discriminating between clinically normal adults with and without subjective cognitive impairment (SCI)
Dr. Dessa Sadovnick
Gene discovery in late-onset AD and related dementia
2008
Dr. Blair Leavitt
SV40 T antigen transgenic mice: A model for defining the role of the cell cycle in Alzheimer's plaque and tangle pathology
Dr. Jane Roskams
Is the neural stem cell niche present and active in Alzheimer’s disease brain?
Dr. Teresa Liu-Ambrose
Enhancing cognition and functional independence in senior women with mild cognitive impairment
2006
Dr. A. Jon Stoessl
Overlapping syndromes resulting in dementia
Dr. Shernaz X. Bamji
The role of β-catenin stabilization in synaptic pathology of Alzheimer's disease
Dr. Mirza Faisal Beg
Improving sensitivity of early detection via multi-dimensional analysis of longitudinal MR scans
Dr. Max Cynader / Dr. William Jia
Progranulin and its potential for a neuroprotective role in dementia
Dr. Liisa Galea
Effects of estrogens on neurogenesis in the adult hippocampus in young and aged rodents
Dr. James McLarnon
Pharmacological modulation of an activated microglia-perturbed vasculature model
Dr. Christopher A. Shaw
Role of progranulin in brain function and neuroprotection
Dr. Cheryl Wellington
The role of ABC cholesterol transporters in metabolism of amyloid precursor protein and ApoE
+$ Million
directly invested in dementia research. +$ Million
co-invested with funding partners. Projects
actively funded towards a cure. Donate
Explore ways to support our mission.
Impact
Discover our latest research projects.
Contact
Have questions or need assistance?